作者： 薛瑜¹，聂敏¹，王鸥¹，王春艳²，韩桂艳³，沈蔷⁴，邓红月⁴，姜艳¹，李梅¹，夏维波¹，邢小平¹，徐苓⁵ （1 中国医学科学院北京协和医学院北京协和医院内分泌科国家卫生和计划生育委员会内分泌重点实验室； 2 航空总医院内分泌科； 3 承德医学院附属医院内分泌科； 4 北京市东城区社区卫生服务管理中心； 5 中国医学科学院北京协和医学院北京协和医院妇产科）

出处： 中华医学杂志 2018 第98卷 第18期 P1408-1413

关键词： 辅肌动蛋白；多态性,单核苷酸；绝经后期；肌肉强度

摘要： 目的探究α-辅肌动蛋白3(ACTN3)基因多态性与绝经后女性肌肉强度的相关性。方法纳入北京市东城区34个社区598例绝经后女性,年龄(62.9±7.0)岁。通过Sequenom Mass Array平台对ACTN3基因rs540874、rs618838、rs2229456位点进行基因分型,并分析其与 ...

作者： Hanhua Ji;Yang Li;Zeyuan Fan;Bo Zuo;Xinwen Jian;Li Li;Tao Liu （Civil Aviation General Hospital, Civil Aviation Clinical Medical College of Peking University Peking University Third Hospital）

出处： BMC Cardiovascular Disorders 2017 Vol.17 No.1

关键词： Monocyte to lymphocyte ratio;Coronary artery disease;Syntax score

摘要： Background We aimed to explore whether monocyte to lymphocyte ratio (MLR) provides predictive value of the lesion severity in patients with coronary ...

作者： Ma SY;Guo YY;Wang SX;Shi JX;Liu J;Liu JF;Zhu P. （1 Department of Geriatric Cardiology, Chinese PLA General Hospital. 2 Department of Cardiovascular Medicine, Shijingshan Teaching Hospital of Capital Medical University. 3 Department of Cadre Clinic, Chinese PLA General Hospital. 4 Department of Geriatrics, Civil Aviation General Hospital.）

出处： Tohoku J Exp Med 2017 Vol.241 No.4 P297-308

关键词： coronary artery disease;ligase detection reaction;pigment epithelium-derived factor;risk factor;single nucleotide polymorphisms

摘要： Coronary artery disease (CAD) is a multifactorial disease with a genetic component. Pigment epithelium-derived factor (PEDF) exerts anti-inflammatory, ...

作者： Chen Z;Liu C;Zhang J;Relkin N;Xing Y;Li Y. （1 Department of Neurology, Aviation General Hospital of China Medical University & Beijing Institute of Translational Medicine, Chinese Academy of Sciences, No. 3 Anwai Beiyuan Road, Chaoyang District, Beijing, 100012, China. 2 Department of Neurology and Neuroscience, Weill Medical College of Cornell University, Cornell Memory Disorders Program, 428 East 72 Street, Suite 500, New York, NY, 10021, USA. 3 Department of Neurology, Aviation General Hospital of China Medical University & Beijing Institute of Translational Medicine, Chinese Academy of Sciences, No. 3 Anwai Beiyuan Road, Chaoyang District, Beijing, 100012, China. drxingyan@163.com. 4 Department of Neurology, Peking Union Medical College Hospital, Beijing, China. doctorliyf@163.com.）

出处： Fluids Barriers CNS 2017 Vol.14 No.1 P13

关键词： Alzheimer’s disease;CSF biomarkers;Idiopathic normal-pressure hydrocephalus;Meta-analysis;Systematic review

摘要： OBJECTIVES: The purpose of this systematic review and meta-analysis was to evaluate the performance of cerebrospinal fluid (CSF) beta amyloid 42 (Aβ42 ...

作者： Wang Y;Harrington OD;Wang Y;Murray CK;Hamblin MR;Dai T. （1 Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School; Department of Medical Oncology, Beijing Institute of Translational Medicine, Chinese Academy of Sciences; Cancer Center, Aviation General Hospital, Beijing. 2 Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School. 3 Infectious Disease Service, Brooke Army Medical Center. 4 Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School; TDAI@mgh.harvard.edu.）

出处： J Vis Exp 2017 No.122

摘要： Burn infections continue to be an important cause of morbidity and mortality. The increasing emergence of multidrug-resistant (MDR) bacteria has led t ...

作者： Gao F;Chen N;Sun W;Wang B;Shi Z;Cheng L;Li Z;Guo W. （1 Centre for Osteonecrosis and Joint-Preserving & Reconstruction, Department of Orthopedic Surgery, Beijing Key Laboratory of Arthritic and Rheumatic Diseases, China-Japan Friendship Hospital, National Health and Family Planning Commission of the People's Republic of China, Beijing, 100029, China. 2 Department of Internal Medicine, Peking University Civil Aviation General Hospital, Beijing, 100123, China. 3 Centre for Osteonecrosis and Joint-Preserving & Reconstruction, Department of Orthopedic Surgery, Beijing Key Laboratory of Arthritic and Rheumatic Diseases, China-Japan Friendship Hospital, National Health and Family Planning Commission of the People's Republic of China, Beijing, 100029, China. 18811796409@163.com.）

出处： Sci Rep 2017 Vol.7 No.1 P2106

摘要： Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess ...

作者： Zhang L;Ding X;Wu Z;Qian X;An J;Tian M. （1 Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, No.95, Yong'an Road, Xicheng District, 100050 Beijing, China. 2 Department of Rehabilitation Medicine, Shandong Provincial Hospital Affiliated to Shandong University, No.324, Jingwu Road, Jinan, Shandong Province, 250021 Jinan, China. 3 Department of Anesthesiology, Pain Medicine & Critical Care Medicine, Aviation General Hospital of China Medical University, No.3, Beiyuan Road, 100012 Beijing, China.）

出处： Pain Physician 2017 Vol.20 No.2 P53-68

摘要： BACKGROUND: Chronic pain often results in cognitive impairment. Our previous study showed that trigeminal neuralgia induced by cobra venom leads to sp ...

作者： Xin-ying ZHENG;Ya-rong ZHANG;Bao-rong ZHANG （a Department of Stomatology, Aviation General Hospital, Beijing 100012, China b Department of Stomatology, West China School of Stomatology, Sichun University, Chengdu 610041, China）

出处： Transactions of Nonferrous Metals Society of China 2017 Vol.27 No.5 P1071-1080

关键词： Ti6Al7Nb alloy;ion implantation;diamond-like carbon coating;fretting wear behavior

摘要： The tribology behaviors of Ti6Al7Nb, its alloy with N-ion implantation, and its alloy with diamond-like carbon (DLC) coating were investigated in arti ...

作者： Wang B;Wang S;Liang G;Xu J;Zhou R;Zhang Q. （1 1 Department of Clinical Laboratory, Aerospace Central Hospital, Beijing, China. 2 2 Department of Clinical Laboratory, Civil Aviation General Hospital, Beijing, China. 3 3 Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Clinical Laboratory, Peking University Cancer Hospital & Institute, Beijing, China. 4 4 Department of Cell Biology, School of Basic Medical Sciences, Peking University, Beijing, China.）

出处： Tumour Biol 2017 Vol.39 No.6

关键词： Lysosomal protein transmembrane 4 beta;pancreatic carcinoma;polymorphism;susceptibility

摘要： Pancreatic carcinoma is an aggressive malignancy with particularly low 5-year survival rate. In order to improve the dismal survival rate, identificat ...

作者： Zhou L;Liu S;Han M;Feng S;Liang J;Li Z;Li Y;Lu H;Liu T;Ma Y;Cheng J. （1 1 Beijing Ditan Hospital, Peking University Teaching Hospital, Beijing, China. 2 2 Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China. 3 3 Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China. 4 4 Division of Infectious Disease, Civil Aviation General Hospital, Beijing, China.）

出处： Tumour Biol 2017 Vol.39 No.2

关键词： AKT1;Apoptosis;autophagy;cell-cycle arrest;microRNA 185

摘要： Studies have demonstrated that microRNA 185 may be a promising therapeutic target in liver cancer. However, its role in hepatocellular carcinoma is la ...