作者： Naveed M;Wenhua L;Gang W;Mohammad IS;Abbas M;Liao X;Yang M;Zhang L;Liu X;Qi X;Chen Y;Jiadi L;Ye L;Zhijie W;Ding CD;Feng Y;Xiaohui Z. （1 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, 211198, PR China; Department of Surgery, Aviation General Hospital, Beijing, 100012, PR China. 2 Department of Surgery, Aviation General Hospital, Beijing, 100012, PR China. 3 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, 211198, PR China. 4 Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, PR China. 5 Children's Hospital of Zhengzhou, Zhengzhou, Henan Province, 450053, PR China. 6 University of Traditional Chinese Medicine, Taiyuan, Shanxi Province, 030600, PR China. 7 Department of National Training Base for Talents in Life Science and Technology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, PR China. 8 Department of Immunology, Peking Union Medical College, Beijing, 100032, PR China. 9 Department of Pharmaceutical Preparation Section, The 3rd Peoples of Wuxi, Wuxi, Jiangsu Province, 214000, PR China. 10 Key Laboratory of Semiconductor Materials Science, Institute of Semiconductors, Chinese Academy of Sciences, Beijing, 100083, PR China. Electronic address: wangzj@semi.ac.cn. 11 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, 211198, PR China. Electronic address: chdd9968@aliyun.com. 12 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, 211198, PR China. Electronic address: yufengcpu@163.com. 13 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, 211198, PR China; Department of Heart Surgery, Nanjing Shuiximen Hospital, Nanjing, Jiangsu Province, 210017, PR China; Deprtment of Cardiothoracic Surgery, Zhongda Hospital Affiliated to Southeast University, Nanjing, Jiangsu Province, 210017, PR China. Electronic address: zhxh@cpu.edu.cn.）

出处： Biomed Pharmacother 2017 Vol.95 P701-710

关键词： B-type natriuretic peptide;Heart failure;Hemodynamics;Myocardial infarction;Salvia miltiorrhiza;Ventricular restraint (ASD)

摘要： A novel ventricular restraint is the non-transplant surgical option for the management of an end-stage dilated heart failure (HF). To expand the thera ...

作者： Naveed M;Hejazi V;Abbas M;Kamboh AA;Khan GJ;Shumzaid M;Ahmad F;Babazadeh D;FangFang X;Modarresi-Ghazani F;WenHua L;XiaoHui Z. （1 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, Nanjing 211198, PR China; Department of Urology Surgery, Aviation General Hospital, Beijing 100012, PR China. 2 Tabriz University of Medical Sciences, Tabriz, Iran. 3 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, Nanjing 211198, PR China. 4 Department of Veterinary Microbiology, Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam 70060, Pakistan. 5 Department of Pharmacology, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, Nanjing 210009, PR China. 6 Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore 54770, Pakistan. 7 Department of Poultry Science, Institute of Animal and Dairy Sciences, University of Agriculture Faisalabad, Faisalabad 38040, Pakistan. 8 Avian Diseases Research Center, Faculty of Veterinary Medicine, Shiraz University, Shiraz, Iran. 9 Department of Chemistry, College of Environmental Sciences, Nanjing Xiaozhuang University, Jiangsu Province, Nanjing 211171, PR China. 10 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: faezeh.modarres@gmail.com. 11 Department of Urology Surgery, Aviation General Hospital, Beijing 100012, PR China. Electronic address: liwenhua361@sina.com. 12 Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Jiangsu Province, Nanjing 211198, PR China; Department of Heart Surgery, Nanjing Shuiximen Hospital, Jiangsu Province, Nanjing 210017, PR China; Department of Cardiothoracic Surgery, Zhongda Hospital affiliated to Southeast University, Jiangsu Province, Nanjing 210017, PR China. Electronic address: zhxh@cpu.edu.cn.）

出处： Biomed Pharmacother 2017 Vol.97 P67-74

关键词： Anti-hypertension;Antioxidant;Clinical pharmacology;Food additive;Green coffee extract;Medicinal values

摘要： Phenolic acids have recently gained substantial attention due to their various practical, biological and pharmacological effects. Chlorogenic Acid (CG ...

作者： 潘昱，仇琪，任卫红，玉献鹏，李全，任学军 （首都医科大学附属北京安贞医院心内科；首都医科大学附属北京安贞医院临床药理中心；中国医科大学航空总医院病理科）

出处： 中华医学杂志 2017

关键词： 冠状动脉疾病；无保护左主干病变；心室功能障碍；左；左心室射血分数；药物洗脱支架

摘要： 目的分析无保护左主干（ULM）病变合并左心室收缩功能不全（LVSD）患者行药物洗脱支架（DES）植入术后的临床特点及预后。方法2005年1月至2012年1月入住北京安贞医院心内科的ULM病变行DES植入术患者511例。根据左心室射血分数（LVEF）将其分为3组，LVEF≤40％组104例，41％~〈 ...

作者： 谷晓广^1,2，续言凤^1,2，王艺萌^1,2，董晓龙^1,2，刘永生^1,2 （1 航空总医院皮肤科； 2 中国科学院北京转化医学研究院）

出处： 第二军医大学学报 2017 第38卷 第10期 P1293-1297

关键词： Sézary综合征；独立生长因子1；干扰素α-2b；细胞凋亡

摘要： 目的 检测独立生长因子1(GFI-1)在Sézary综合征患者和正常人外周血中的表达,为开发针对GFI-1基因靶点的治疗提供实验依据。方法 利用流式细胞术分离纯化7例Sézary综合征患者外周血中CD4+CD7-的Sézary细胞(SS细胞)作为实验组,以10例正常人外周血CD4+T细胞、Sézar ...

作者： Zhao C;Gao Y;Zhao L;Li Y;Zhang Y;Wang S;Zhang H;Lu G;Guo X. （1 Department of Endocrinology, Peking University First Hospital, No. 8 Xi Shi Ku Street, Xi Cheng District, Beijing 100034, China. 2 Department of Endocrinology, Civil Aviation General Hospital, No. 1 Gao Jing Jia Street, Chao Yang District, Beijing 100123, China. 3 Department of Endocrinology, Peking University First Hospital, No. 8 Xi Shi Ku Street, Xi Cheng District, Beijing 100034, China. Electronic address: emilyzy14@sina.com. 4 Department of Pathology, Peking University First Hospital, No. 8 Xi Shi Ku Street, Xi Cheng District, Beijing 100034, China.）

出处： Int Immunopharmacol 2017 Vol.44 P53-60

关键词： Hashimoto's thyroiditis;IgG;Neonatal Fc receptor;TgAb;Th1/Th2 cytokines

摘要： OBJECTIVE: Thyroglobulin (Tg) and thyroid peroxidase (TPO) antibodies (TgAb and TPOAb), which are primarily of the immunoglobulin G (IgG) class, can m ...

作者： Sun J;Gao X;Meng D;Xu Y;Wang X;Gu X;Guo M;Shao X;Yan H;Jiang C;Zheng Y. （1 Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. 2 Department of Anesthesiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China. 3 Department of Neurosurgery, Aviation General Hospital of China Medical University, Beijing, China. 4 Department of Urology, Cancer Hospital of Harbin Medical University, Harbin, China. 5 Department of Neurosurgery, Heilongjiang Provincial Hospital, Harbin, China. 6 Department of Head and Neck Surgery, Cancer Hospital of Harbin Medical University, Harbin, China. 7 School of Basic Medical Sciences, Harbin Medical University, Harbin, China. 8 Department of Pediatric Hematology, Peking University International Hospital, Beijing, China.）

出处： Cell Physiol Biochem 2017 Vol.43 No.2 P636-643

关键词： Cofilin;Epilepsy;Hippocampus;Limk1;MiR-134

摘要： BACKGROUND: MiR-134 is enriched in dendrites of hippocampal neurons and plays crucial roles in the progress of epilepsy. The present study aims to inv ...

作者： 张强，刘士博，杨军星，韩佳岐，宋立杰，徐一驰，王瑶，赵楚翘，王博蔚，刘志辉 （吉林大学口腔医院修复科；民航总医院口腔科；吉林大学第二医院妇产科）

出处： 吉林大学学报(医学版) 2017 第43卷 第4期 P839-844

关键词： 海藻酸 壳聚糖 血管内皮生长因子 万古霉素 缓释 微球

摘要： 目的：制备载有血管内皮生长因子(VEGF)和万古霉素(VAN)的多层海藻酸盐-壳聚糖缓释微球，探讨其体外释放特性。方法：采用乳化交联和层层自组装技术制备微球;正交实验设计考察海藻酸钠浓度、氯化钙(CaCl 2 )浓度、油水比及span80浓度对VEGF和VAN包封率(EE)和载药量(DL)的影响，以 ...

作者： Wang P;Li M;Dong L;Chen H;Su W;Wang YP. （1 Cardiovascular Center, Affiliated Friendship Hospital, Capital Medical University, Beijing, 100050, P. R. China. 2 Heart Department, Affiliated Daxing Hospital, Capital Medical University, Beijing, 100026, P. R. China. 3 Heart Department, Civil Aviation General Hospital, Beijing 100123, P. R. China. 4 Cardiovascular Center, Affiliated Friendship Hospital, Capital Medical University Beijing, 100050, P. R. China. 5 Cardiovascular Department, Affiliated Liangxiang Hospital, Capital Medical University 102401, P. R. China. 6 Healthcare Medical Center, Affiliated Friendship Hospital, Capital Medical University 100050, Beijing, P. R. China.）

出处： Exp Clin Endocrinol Diabetes 2017

摘要： Relaxin (Rlx) is known to antagonize diabetic cardiac fibrosis. However, its mechanism is poorly understood. Protein kinase Cδ (PKCδ) plays a crucial ...

作者： 郑新颖，张雅蓉，张保荣 （航空总医院口腔科；航空总医院口腔科；四川大学华西口腔医学院口腔科）

出处： 中国有色金属学报 2017 第27卷 第5期 P1071-1080

关键词： Ti6Al7Nb合金；离子注入；DLC涂层；微动磨损行为

摘要： 通过往复滑动微动磨损实验研究Ti6Al7Nb合金、氮离子注入Ti6Al7Nb合金、DLC涂层Ti6Al7Nb合金在人工唾液环境下的磨损性能。运用 X射线衍射分析、拉曼光谱分析、三维轮廓分析、扫描电镜形貌和摩擦动力学行为分析等方法,详细讨论了表面改性层的磨损特性。结果表明:随着氮离子浓度的增 加,Ti ...

作者： Wenjuan Wang;Guangxia Cui;Biao Jin;Ke Wang;Xing Chen;Yu Sun;Lihua Qin;Wenpei Bai （a Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China b Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China c Obstetrics and Gynecology Department, Civil Aviation General Hospital, No. 1 Gaojingjia Street, Chaoyang District, Beijing, China d Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China）

出处： Ann Anat 2016 Vol.208 P31-39

关键词： Dorsal raphe (DR);Estradiol valerate;Ovariectomy;Preoptic anterior hypothalamus (POAH);Remifemin;Serotonin pathway

摘要： Perimenopausal syndromes begin as ovarian function ceases and the most common symptoms are hot flushes. Data indicate that the projections of serotoni ...